Asociación entre troponina y perfil lipídico Niveles en pacientes con insuficiencia cardíaca crónica / Association between Troponin and Lipid Profile Levels in Patients with Chronic Heart Failure

Background: Older women have a high chance of suffering from coronary heart diseases and heart failure. Possessing high-sensitive tests will permit early detection of cardiac troponin and lipid proteins (HDL, LDL, VLDL, & Triglyceride) I in levels that are below the diagnostic endpoint for the acute coronary syndrome. Aim of the study: The intent in this study is to analyze the association among the 3 ranks taking into consideration any future cardiac happening within the community setting and involving elderly women who are aged seventy years and above. Patients and Methods: 212 women were grouped for this study, and this lot was lacking any CHD within the set baseline or the troponin and lipid proteins (HDL, LDL, VLDL, & Triglyceride) established above the analytical limits for the disease to be studied (acute coronary syndrome). These elderly women had a 15-year continuation of hospitalization and mortality measures. Results: The analysis showed 22 percent of the study group to be suffering from CHD, there was 15 percent of myocardial infarction or death brought about by CHD, and 10 percent of the heart failure. The 99 percent of assessed serum illustrations, troponin, and lipid proteins (HDL, LDL, VLDL, & Triglyceride) levels were above recognition. Taking into consideration of the Framingham risk features, the correction done for each SD normal linear changed troponin and lipid proteins (HDL, LDL, VLDL, & Triglyceride) upsurge was connected to an upsurge uncertainty for the coronary heart disease. Conclusions: conclusively, the troponin and lipid profile (HDL, LDL, VLDL, & Triglyceride) I am autonomously linked with the foreseeable cardiac happenings in older women across Iraq without seeming clinical indicators. Adding cardiac troponin and lipid proteins (HDL, LDL, VLDL, & Triglyceride) 1 to the conventional risk factor can greatly enhance the risk prediction in this background.

Association of the ATP-binding Cassette Transporter A1 Gene Polymorphismo with Lipid Profile and Tye 2 Diabetes Mellitus

Diabetes remains unique among the main non-communicable ailments (NCDs) recognized by the World Health Organization (WHO), apart from the circulatory diseases, tumours, and long-lasting respiratory ailments. The current study aimed to determine the correlation between ABCA1 gene polymorphismo and lipid profile in type 2 diabetes mellitus patients. Serum samples from 100 type 2 diabetes mellitus patients (46 males and 54 females) and 50 standard subjects (26 males and 24 females) were colected from Najaf province/Irak. Fasting blood sugar (FBS), and lipid profiles (total cholesterol (TC), triglycerides (TH), HDL, LDL, and VLDL) were meassured. Plymerase chain reaction (PCR) with the Taq1 enzye was used for the amplification of the ABCA1 gene, which contains 525bp of the AABCA1 gene in the locus V825I. The present study revaled a positive corrrelation between FBS and body mass index (BMI) (r= 0.2390, p= 0.0463), TG (r = 0.1836, p= .01743), and VLDL (r = 0.1836, p = 0.1839). The frequencies of the GG genotype and the G allele were higher in the normal groups compared to the patientes (58% vs. 56% and 70% vs. 67%, respectively); conversely, the frequencies of the AA genotype (18% vs. 22%) and the A allele (30% vs. 33%) were higher in the patients compared to the normal groups. The data also showed a significant relationship between ABCA1 gene polymorphim and both TG and VLDL (P=0.007 for cach). There is relationship between the ABCA1 gene and HDL level. Additiionally, the G allele could be a defensive factor against diabetes mellitus in Iraqi peole (AU)